Missing link between dinosaur nests and bird nests

first_imgThe links between dinosaurs and birds keep getting stronger: skeletal structures, feathers—and now nests. Whereas some dinosaurs buried their eggs crocodile-style, a new analysis suggests that other dinosaurs built open nests on the ground, foreshadowing the nests of birds.Interpreting the fossil record is always tough, but analyzing trace fossils such as nests is especially daunting. Those structures, and the materials used to make them, usually aren’t preserved, says Darla Zelenitsky, a paleobiologist at the University of Calgary in Canada. When paleontologists do find a nestlike structure that includes material such as sticks or other vegetation, the question arises: Was this stuff part of the original nest, or just carried there with the sediment that buried the nest and helped preserve it?To gain insight into dinosaur nesting habits, Zelenitsky and her colleagues studied the most durable parts of nests—the eggs themselves. (Being largely made of the mineral calcium carbonate, they’ve got a head start on fossilization and are sometimes incredibly well preserved.) In particular, the team looked at the size and arrangement of small pores in the ancient shells, because those details are telling in modern creatures.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*) Kohei Tanaka In crocodiles’ buried nests, the heat needed to incubate the eggs comes from decomposition of overlying organic matter or the sunlight absorbed by the soil. Plus, in buried nests airflow is somewhat limited, thus requiring eggs to be relatively porous to help increase the flow of oxygen into and carbon dioxide out of the eggs. But birds that brood in open nests can get by laying eggs with fewer or smaller pores.So the team compared the porosity of eggshells from 29 species of dinosaurs (including large, long-necked herbivores called sauropods; bipedal meat-eaters called theropods; and duck-billed dinosaurs) with that of shells from 127 living species of birds and crocodiles.Most of the dinosaur eggs were highly porous, suggesting that they buried their eggs to incubate them, the researchers report online today in PLOS ONE. But some of the dinosaur species in one group—a subset of well-evolved theropods considered to be the closest relatives of modern-day birds—laid low-porosity eggs, which suggests they incubated their eggs in open nests.“This is a well done paper; the results make a lot of sense,” says Luis Chiappe, a vertebrate paleontologist at the Natural History Museum of Los Angeles County in California. The findings, he says, line up other studies suggesting that some birdlike dinosaurs were warm-blooded, which would have enabled them to incubate eggs in an open nest rather than depend on rotting vegetation or sunlight. Chiappe adds that the trend toward open nests could have allowed some dinosaurs to take another step toward birdlike nesting by moving their nests into the trees.But considering only two types of nests—open versus buried—may be too simplistic, suggests Anthony Martin, a paleontologist at Emory University in Atlanta. Some dinosaurs—like a few of today’s birds—may have nested in burrows, which could have offered the stable temperature and protection from predators of a buried nest but resulted in low-porosity shells. Also, covered nests come in different types: Loose vegetation piled atop a buried nest can have a lot of airflow through it, allowing eggs to have relatively small pores, whereas eggs buried in soil or similar materials might not breathe as well and thus require larger pores, he notes. Nevertheless, Martin adds, the team’s study “is a good first start toward answering the question about what early dinosaur nests looked like.”center_img A nest of fossilized eggs from an oviraptorid dinosaur of the Late Cretaceous period. last_img read more

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Freelancer/Independent Worker/Other: What Do You Call Yourself?

first_img“A rose by any other name would smell as sweet” – William ShakespeareFreelancer, solopreneur, consultant, independent contractor.These are just a few of the names that independent workers use to describe themselves to their peers and the world at large.As the economic landscape continues to expand and support non-traditional employment, it’s important that we begin to recognize independent workers of all types, levels and across all industries. After all we’re in the same boat; shouldn’t we band together to fight for the acknowledgement and protections we all deserve?Words have power, and how we classify ourselves can change how others view us.What do you call yourself? Why?last_img read more

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Chandimal banned for one Test after being found guilty of ball-tampering

first_imgSri Lanka skipper Dinesh Chandimal has been banned for one Test and fined 100 per cent of his match fee after being found guilty of ball-tampering during the second Test against West Indies at St Lucia.Chandimal had been charged with trying to change the condition of the ball but he had denied the charges. He has been charged for breaching Level 2.2.9 of the Code of Conduct by ICC.”During a hearing held at the end of the St Lucia Test, in which video evidence was used in the presence of the Sri Lanka team management as well as the match officials, Chandimal admitted putting something in his mouth but wasn’t able to recall what it was,'” an ICC press release said on Tuesday.Also read – Chandimal pleads not guilty to ball-tampering chargesThe release further stated that Javagal Srinath, who was the match referee, ” handed Chandimal the maximum punishment available under the code, i.e. two suspension points and a fine of 100 per cent of his match fee.”As two suspension points equate to a ban from one Test or two ODIs or two T20Is, whatever comes first for the player, Chandimal will miss the day/night Barbados Test, starting from Saturday, 23 June. Furthermore, and because two suspension points correspond to four demerit points, these have been added to Chandimal’s disciplinary record.Commenting on his decision, Mr Srinath said: “After reviewing the footage of the incident, it is clear that Dinesh applied an artificial substance to the ball, namely saliva containing the residue of something he had in his mouth, an action which is prohibited under the ICC Code of Conduct.advertisementAlso read – Sri Lanka players walk off to protest ball-tampering allegations”The footage shows that upon receiving the ball, Dinesh took something from his pocket and put it into his mouth. After sucking or chewing whatever he put in his mouth for a few seconds, Dinesh then proceeded to spit on his finger and polish the ball with his saliva which would have contained the residue of the artificial substance that he had in his mouth, on two separate occasions.””During the hearing, Dinesh admitted to putting something in his mouth but couldn’t remember what it was, which I found unconvincing as a defence and the fact remains it was an artificial substance.Also read – Sri Lanka deny wrongdoing in 2nd Test vs West Indies”In the pre-series briefing held on the back of the ICC Cricket Committee recommendations, both the sides were explicitly told that the match officials would be extra vigilant towards all aspects of fair play, including changing the condition of the ball and as such it is disappointing that this has happened.”ICC Chief Executive David Richardson backed the Playing Control Team, when he said: “The ICC fully supports the match officials in their decision and will continue to do so in any other such instances.”The strong message from last month’s ICC Cricket Committee was that there needs to be stiffer sanctions for offences such as changing the condition of the ball and, as such, we will be recommending to the ICC Board at next month’s annual conference in Dublin to upgrade this to a Level Three offence.”On Sunday, Chandimal had pleaded not guilty after on-field umpires Aleem Dar and Ian Gould, and third umpire Richard Kettleborough, all from the Emirates Elite Panel of ICC Umpires, had charged him for changing the condition of the ball in breach of clause 41.3 of the ICC Standard Test Match, ODI and T20I Playing Conditions after play on Saturday.The umpires had laid the charge after television footage from the final session’s play on Friday, which had been made available before the start of play on Saturday, appeared to show the Sri Lanka captain taking something out from his left pocket and putting it in his mouth, before applying the residue of the artificial substance to the ball which they viewed as an attempt to change its condition.(With inputs from ICC)last_img read more

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Travis Ford Will Be Fired and That’s Not Really Something to Celebrate

first_imgI didn’t know whether I should write this post at the risk of sounding sufficiently sanctimonious about OSU hoops and sports generally. As if I’m operating on a different plane than others when it comes to the way I consume my diet of college athletics.But I also think it needs to be said so I apologize if it’s dripping with the smugness of a self-satisfied blogger who has watched almost every game Travis Ford has ever coached.Travis Ford is about to get fired. If you don’t think that’s about to happen after all the chatter, the 20-loss season, the unrest among fans, the emptiness of GIA and the final nail in the coffin from Eddie Sutton himself then you’re simply not living in reality.Travis Ford will not be the basketball coach at Oklahoma State in a week or a month or whenever Mike Holder decides to light fire to $7 million (less whatever Travis Ford makes at his next job).And certainly there’s a need for some fresh air. I, like many of you, have felt suffocated by the $20 million noose hanging around the neck of GIA for the last few years. There was an inevitability to the whole thing that was (and is) unfortunate.Travis Ford is going to be fired because he lost 20 games for the fourth time in OSU’s 107-year history. He’s going to be fired because he went 15-54 on the road in the Big 12 over eight seasons. He’s going to be fired because he won a single game in the NCAA Tournament over eight years.He’s going to be fired because he finished in the top half of the Big 12 one time. He’s going to be fired because he couldn’t get Markel Brown, Marcus Smart and Le’Bryan Nash out of the first round in two tries (!) He’s going to be fired because going 155-111 in eight years is just not good enough in Stillwater. And he’s going to be fired (mostly) because attendance has gone the way of oil in northern Oklahoma. From the Tulsa World:In 2008-09, Ford’s first season, Oklahoma State generated $4.65 million in men’s basketball ticket sales, according to the financial reports Oklahoma State must file with the NCAA. Last year, when OSU reached the NCAA Tournament and averaged 7,897 fans per home game, ticket-sales revenue was $2.46 million.That’s a drop of 47.1 percent, or $2.19 million.And it will be even worse when this year’s report comes out. Here’s more:Oklahoma State’s average attendance this season — 5,857 — ranked 58th of 65 Power 5 teams. And in just the past two seasons — from Marcus Smart’s sophomore year to this 12-19 campaign — attendance plummeted 43.7 percent.So the reasons Travis Ford will be fired are myriad which is usually the case when it comes to firings for on-court performance. There’s not one thing. There are many, many things.And yet, as I noted here, Ford didn’t quit. His players didn’t quit. They galloped for him until the bitter end. He didn’t have proper horses. But they still galloped hard.“He’s always been positive the whole year,” said Jeffrey Carroll on Wednesday after the final game of the Ford era. “Great coach, I love him to death. He has made me a totally better player this year. And like just as a team, we’ve grown together as one. So I think this season has made us a lot closer.”I had breakfast with a buddy on Thursday morning here in Dallas. We don’t really talk much sports usually, but he asked how this blog was going and we sort of got into the Travis Ford thing a little bit. I told him I felt bad calling for the job of someone I don’t interact with and don’t know. It seems like it should be easier but somehow it has become difficult.He said something interesting. He said he thinks coaches (and high-level executives in general) make a ton of money because nobody wants those jobs. Nobody wants to be publicly scorned because they’re doing a slightly below average job.[1. Side note here: Is sports the only industry where the folks who hold the power of hiring and firing make significantly less money than the people they are hiring and firing? That’s pretty strange, right?]Rick in accounting doesn’t want to be ridiculed on Twitter because he incorrectly performed a VLOOKUP on Monday afternoon. And so the money offers a sort of alleviation for all the stressors that come with being a public figure.And I think people think that being paid a lot of money to not do your job (i.e. a buyout) sounds like the best outcome in the world. But it’s not. How could it be? Somebody is about to say, “you are so bad at your job that we will literally give you $7 million (less what you earn somewhere else) to not do your job anymore.” That’s a blow to the ego of anyone who finds an iota of identity in the work they do or prides themselves on their professional effort (so it’s a blow to the ego of every human).Not only that, but as several people mentioned, when you get fired you’re forced to uproot your family and your kids in high school and middle school and hit restart and make new friends and yeah, nobody wants to do stuff like that.I’m not trying to pass the hat for a millionaire here but rather recognize the fact that Travis Ford is a real human being and he has emotions and feelings that aren’t directly tied to the size of his paycheck. I think sometimes we mitigate the reality of the lives of others based on how much money they make and think that number justifies our celebration of their dismissal within their profession. It doesn’t … or it shouldn’t.OK, I think that’s the end of my rant.Travis Ford should (and will) be fired by Oklahoma State soon and I’m sad about that for him and his family and everyone involved with Oklahoma State basketball.Not just about Ford. There are support staff folks who will be moving on as well w/o a buyout. Humans with feelings are impacted here.— thinks we go 8-4 guy (@Pokelahoma) March 10, 2016But I also think that sadness can co-exist with an excitement of what lies on the other side of the next few weeks. The future of Oklahoma State hoops is about to be bright because it always is when a new coach is hired and new idealogical views are put forth. I’m glad for that, I really am. And we will chat more about that soon (very soon, I believe).So for now, I’m bummed about the Ford era, hopeful for the future and understanding of why Mike Holder inked that 10-year deal. Because seven years ago he saw in Ford an unrelenting spirit that he wanted to sign up for. It’s been clear that Ford’s players would do pretty much anything for him and Mike Holder saw that. I can see why now.“People have asked me about it, and they don’t understand the life I live,” Ford said on Wednesday after his last loss. “They don’t understand — they are not around me enough to know my mindset of how I work. I immerse myself into trying to figure out how to help this team every way possible, and, you know, I haven’t really — you know, I put everything I could in trying to figure out how to beat K-State. And now I am thinking about what I could have done differently.”The unfortunate reality is a complex one but it hinges on a simple truth: the whole thing just didn’t work the way it should have. Ford didn’t live up to the average expectation for Oklahoma State hoops and he and everyone else knows it. That’s OK.[1. Easy for me to say because I don’t have to pay him $7 million minus what he makes somewhere else!] It’s time to move on. And I wish Travis Ford the best. He brought at least a little magic to the Old Lady and delivered several great moments (the Smart backflip, Memphis at home, that first NCAA tournament game, every Kansas home game).Not enough to make it until the end though.RIP the Travis Ford era.If you’re looking for the comments section, it has moved to our forum, The Chamber. You can go there to comment and holler about these articles, specifically in these threads. You can register for a free account right here and will need one to comment. If you’re wondering why we decided to do this, we wrote about that here. Thank you and cheers!last_img read more

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Transfer latest: Man Utd go all out for Neymar as he snubs Madrid

first_imgTransfers Transfer news & rumours LIVE: Man Utd to go all out for Neymar as he turns back on Madrid Goal Last updated 1 year ago 23:49 5/19/18 FacebookTwitterRedditcopy Comments(0) Neymar Man Utd Rumour Getty/Goal Transfers Primera División Premier League Bundesliga Ligue 1 Serie A Goal takes a look at the biggest transfer news and rumours from the Premier League, La Liga, Serie A and beyond Man Utd to go all out to sign NeymarNeymar is desperate to leave Paris Saint-Germain in the summer and, having grown tired of waiting for Real Madrid, will now consider a switch to Manchester United, reports Don Balon . Madrid were considered to be the front-runners for the Brazil international’s signature, although he has apparently got fed up of waiting for the Liga giants to make their move.Now, Jose Mourinho and Manchester United will look to do everything they can to get Neymar to Old Trafford, with Alexis Sanchez and Paul Pogba having apparently contacted the 26-year-old about a possible transfer. Article continues below Editors’ Picks Goalkeeper crisis! Walker to the rescue but City sweating on Ederson injury ahead of Liverpool clash Out of his depth! Emery on borrowed time after another abysmal Arsenal display Diving, tactical fouls & the emerging war of words between Guardiola & Klopp Sorry, Cristiano! Pjanic is Juventus’ most important player right now Hoffenheim beat Arsenal to Meyer signingHoffenheim have pulled off a transfer coup by agreeing a deal to sign Schalke midfielder Max Meyer, according to Leipziger Volkszeitung . Meyer is out of contract at Schalke in the summer and has decided to leave, with Arsenal among the clubs to have shown an interest in the Germany international.RB Leipzig were also keen on Meyer, but Hoffenheim have persuaded him to sign after clinching qualification for next season’s Champions League.Roma boss ‘convinced’ Alisson will stayRoma boss Eusebio Di Francesco is hopeful that goalkeeper Alisson will remain with the club through the summer.The 25-year-old shot-stopper is wanted by the likes of Liverpool and Real Madrid, having enjoyed a fine season in the Italian capital.His coach, however, is optimistic that the Brazil international will not depart Italy.Check out the full story right here on Goal ! ‘Real Madrid should not go crazy for Salah’Former Real Madrid star Predrag Mijatovic has cautioned his old club against pursuing Liverpool forward Mohamed Salah, believing they would be better served developing their own young stars.Egypt international Salah has enjoyed a staggering debut season at Anfield, winning the Premier League’s Golden Boot award and spearheading the Reds’ charge to the Champions League final.His form since moving from Roma is rumoured to have caught the interest of Madrid, but Mijatovic would prefer Los Blancos to focus on their emerging crop of talents.Check out the full story right here on Goal ! Benitez would welcome Torres to NewcastleNewcastle boss Rafael Benitez has admitted that he would love Fernando Torres to join him at the club.The 34-year-old striker is an iconic figure in the history of Atletico Madrid but will leave the Spanish side at the end of the season after helping them to win the Europa League.Benitez has worked with Torres previously at Liverpool and Chelsea, and would be eager to be reunited with his countryman once again, even if he admits that it is a long shot.Check out the full story right here on Goal ! Bayern make €60m move for BaileyBayern Munich have put in a €60 million (£52m/$71m) bid for Bayer Leverkusen’s Leon Bailey, reports ESPN . While the Bundesliga champions are eager to sign the winger, his current club are holding out for closer to €100m and would rather sell their prized asset to Real Madrid. Chelsea are also keeping an eye on him.Jorginho subject to €75m bidManchester City have bid €75 million (£65m/$88m) for Napoli midfielder Jorginho, according to Italian broadcaster Radio CRC .The Italy international, 26, is one of the top targets for Pep Guardiola this summer as the Premier League champions aim to become the first side to win back-to-back titles since Manchester United achieved it a decade ago.City eye Iniesta in player-coach roleManchester City are keen to bring Andres Iniesta into the club in a player-coach role, according to Yahoo Sport .Arteta is expected to be confirmed as Arsenal manager in the coming weeks, and will thus vacate his coaching role at the club.Iniesta and City are in talks over a deal, and the Barcelona legend is keen on a move.Herrera hopeful over Manchester United futureAnder Herrera is hopeful he will remain at Manchester United next season, but accepts the club may reinforce their midfield this summer.”My future is the FA Cup final. I want to be here next season and unless the club sack me, I will be here in pre-season and fight to keep adding games to my total,” he said, as quoted by  The Guardian .Read the full story on Goal ! Spurs close in on Barca youngster Riqui PuigTottenham are close to signing Barcelona youngster Riqui Puig, according to Sport .The 18-year-old enjoyed a sparkling season in the UEFA Youth League and, though he has an offer to move into Barca’s B team, Spurs have made contact with the teenager and are hopeful of completing a deal.Marseille would ignore €80m Thauvin bidMarseille would ignore an €80 million offer for Florian Thauvin, according to the club’s president Jacques-Henri Eyraud.The former Newcastle United flop has enjoyed a stunning season in Ligue 1 but the club is in no rush to cash in on him.Read the full story on Goal ! Dembele to ditch Barcelona for PSG Ousmane Dembele is ready to give up on his Barcelona career and wants to negotiate a move to Paris Saint-Germain,  Don Balon  reports.The French winger has struggled with injury and form since his arrival from Borussia Dortmund earlier this season and is ready to start talks with PSG, while Barca are even willing to sell for a cut price of €100 million ($118m/£87m).Dybala emerges as Madrid’s plan BWhile Neymar remains Real Madrid’s top target for the summer, Juventus ace Paulo Dybala has emerged as the club’s secondary option, reports Don Balon . Dybala is on the outs with Massimiliano Allegri, but the Spanish giants will face stiff competition for the Argentine from Bayern Munich, Barcelona and Atletico Madrid. Guardiola wants Kroos at CityPep Guardiola wants to bring Toni Kroos to Manchester City this summer as he attempts to build a team that can challenge for the Champions League title, according to Don Balon . The manager is familiar with the midfielder from their time together at Bayern Munich, but he will face competition from former Real Madrid boss Jose Mourinho, who would like to bring the German to Manchester United. Ramos to join Beckham’s MLS sideSergio Ramos is considering a move to Major League Soccer to join David Beckham’s Miami team when his Real Madrid contract is up, reports Don Balon . The Spanish defender and his former team-mate are still close friends, and Ramos is seriously considering a move to the United States for his twilight years. The Miami side will join MLS in 2020. Moyes tops Stoke’s wishlistDavid Moyes is Stoke’s top choice to lead the club’s promotion chase next season, according to the Mirror . Paul Lambert’s four-month run as the club’s manager came to an end with the Potter’s relegation. Moyes is a free agent after his deal with West Ham ran out this week and Stoke are hoping to land the 55-year-old as the club looks to make a quick return to the Premier League. Agent fee a sticking point on Evans moveThe agent of Johnny Evans wants a £4 million fee ($5m) if he can secure a £3m move to Leicester City for the defender, according to the Daily Mail . Evans has a £3m relegation release clause in his contract, but the large fee for his agent is holding up a move to the Foxes, who are trying to sing him for the third window running. Hart to get Premier League lifelineFormer Manchester City goalkeeper Joe Hart is set to get a Premier League lifeline, with Southampton and Wolves set to offer him a place next season, the Mirror reports. The 31-year-old has been on loan at Torino and West Ham for the last two seasons and was left off England’s World Cup squad for the summer. Saints chasing defensive duoSouthampton are set to bolster their back-line after the winter departure of Virgil van Dijk, reports The Sun .  A £20 million ($27m) move for Middlesbrough defender Ben Gibson is first up, with the club also interested in Swansea’s Alfie Mawson.Everton offer Rooney open-ended returnWayne Rooney is still weighing up the option to join D.C. United in Major League Soccer, but has been given an open-ended invitation to return to Everton as a coach, reports the Daily Mail . The move to MLS will not stop the offer from Rooney, but the chance to stay home and launch his coaching career might impact his decision to move to the United States.last_img read more

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Eliud Kipchoge smashes two-hour marathon barrier

first_img Associated Press ViennaOctober 12, 2019UPDATED: October 12, 2019 14:29 IST Eliud Kipchoge from Kenya celebrates after crossing the finish line. (AP Photo)HIGHLIGHTSEliud Kipchoge has become the first athlete to run a marathon in less than two hoursRunning at a consistent average pace of 2:50 minutes per kilometer (4:33.5 minutes per mile)Kipchoge holds the official world record of 2:01:39 since shattering the previous best mark by 78 secondsEliud Kipchoge has become the first athlete to run a marathon in less than two hours, although it will not count as a world record.The Olympic champion and world record holder from Kenya clocked 1 hour, 59 minutes and 40 seconds Saturday at the INEOS 1:59 Challenge, an event set up for the attempt.Kipchoge was supported by 36 pacemakers who accompanied him in alternating groups, one of the reasons the IAAF will not ratify the time as a world record.Running at a consistent average pace of 2:50 minutes per kilometer (4:33.5 minutes per mile), Kipchoge was 11 seconds ahead of schedule halfway through his run.The pacemakers left him for the final 500 meters, and Kipchoge punched his chest twice in celebration when he finished.The Prater park in the Austrian capital offered long straights, protected from the wind by high trees, for most of the 9.6-kilometer course, which Kipchoge completed more than 4 times.It was his second attempt at breaking the two-hour barrier, after missing out by 26 seconds at a similar event on the Formula One track in Monza, Italy, in May 2017.Kipchoge, who took Olympic gold in Rio de Janeiro in 2016 and has won 10 of his 11 marathons, holds the official world record of 2:01:39 since shattering the previous best mark by 78 seconds in Berlin last year.Also See:For sports news, updates, live scores and cricket fixtures, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for Sports news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted bySaurabh Kumar Tags :Follow Eliud KipchogeFollow Olympic championFollow Kenya Next Eliud Kipchoge smashes two-hour marathon barrierEliud Kipchoge of Kenya became the first athlete ever to run a full 42-km marathon in under 2 hours, completing the race in 1:59:40.advertisementlast_img read more

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Highland Park Illuminates The Light, a 17-Year-Old Single Malt Scotch Whisky

first_img Highland Park Releases 2 New Limited-Release Bottles Editors’ Recommendations All the New Whiskies You Need to Drink This Fall The Best Blended Scotch Whiskies to Add to Your Collection Back in March, we wrote about the first of two special-edition whiskies that were to be released by Scotch whisky company Highland Park in 2018: The Dark, a 17-year-old single malt whiskey aged exclusively in first-fill European oak sherry casks and meant to represent the cold, long autumn and winter seasons on the Orkney Islands. Now that the colder months are (thankfully) behind us, Highland Park has introduced the second in the series: The Light. The Light is a 17-year-old single malt Scotch whisky (just like The Dark) created to represent the spring and summer on Orkney. (Summer days, for those that want a fun fact to break out when opening your very own bottle of The Light, last for 20 hours on Orkney. If you need a second fun fact, you can drop the truth bomb that temperatures generally stay between 60 degrees and 35 degrees Fahrenheit — not too summery, but when the average winter high is around 44 degrees, 60 degrees seems practically sweltering.)Aged entirely in refill American oak casks, The Light has no color added, giving it a light golden hue. On the nose, you’ll find apples and pears mixing with a little bit of oak and a very subtle layer of peat smoke. The fruitiness continues on the palate, with more orchard fruits coming through, this time with vanilla and caramel rounding out the profile. While it is somewhat light and summery, it is still not something to be taken lightly — The Light is 52.9 percent ABV and has some strong pepper and oak notes on the palate to match the light fruit flavors. The finish isn’t quite as long as an Orkney summer day, but it’s close.As we guessed, not only is the whisky a contrast to The Dark, but so is the bottle — the pale green(ish) glass is a stark (and aesthetically-pleasing) antithesis to the black bottle of the first whisky in the series.Highland Park The Light retails for around $300 and can be found online here. If it sounds like a bottle you need to pick up, you’ll want to hurry — only 4,500 bottles were shipped to the United States. Bruichladdich Distillery Unveils its New Octomore Scotch Whisky Series Glenfiddich Grand Cru Makes a French Connection with 23-Year-Old Scotchlast_img read more

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US says Chinas death sentence against Canadian politically motivated

first_imgTORONTO — The U.S. State Department says China’s death sentence against a Canadian man is “politically motivated.”Wednesday’s statement from U.S. deputy spokesman Robert Palladino says that U.S. Secretary of State Mike Pompeo and Foreign Minister Chrystia Freeland spoke Tuesday and “expressed their concerns about the arbitrary detentions and politically motivated sentencing of Canadian nationals.”A Chinese court resentenced Robert Schellenberg to death in a sudden retrial of a drug-smuggling case on Monday.Freeland and Prime Minister Justin Trudeau have been talking to world leaders about Schellenberg’s case and the cases of two Canadians arrested in China in apparent retaliation for the arrest of Chinese Huawei executive Meng Wanzhou.Canada arrested the daughter of Huawei’s founder at the request of the U.S., which wants her extradited to face fraud charges.last_img read more

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Canadians television viewing appetite on the rise

OTTAWA — The CRTC says Canadians spent more time watching television or listening to radio in 2011 than the previous year despite the proliferation of non-traditional media.But they also increased their Internet television watching, to 2.8 hours a week from 2.4 the previous year.Four per cent of Canadians report watching television online, while four per cent said they watched on a smartphone and three per cent on a tablet.The federal regulator says on a weekly basis, Canadians watched an average of 28.5 hours of television, up from 28 hours in 2010.And they listened to an average of 17.7 hours of radio, up from 17.6 hours the previous year.[np-related]The federal regulator says 78% of Canadian households had Internet service in 2011, and the number of subscribers of wireless services grew by six per cent, with newer competitors doubling their market share to four per cent.CRTC chairman Jean-Pierre Blais says in the report that the evidence suggests Canadians are enthusiastic consumers of creative content, whether it is offered on TV, radio or through digital platforms.The regulator says Canada’s telecommunications and broadcasting industries had a strong year in 2011, with consumers spending an average of $180 a month on services.Broadcast revenues climbed 5.5% to $16.6-billion from 2010, and revenues from telecommunications services increased by 2.5% to $42.7-billion.Overall, the communications industry accounted for about 4.6% of Canada’s gross domestic product in 2011.The Canadian Press read more

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Key foreign currency quotations

Quotations for key foreign currencies in terms of the Canadian dollar. Quotations are nominal, for information purposes only.Canadian dollar value on Thursday, the previous day, three-months and one-year: Currency Thu Wed 3 months Year U.S. dollar 1.2946 1.2982 1.3418 1.2959 British Pound 1.6773 1.6774 1.6728 1.6758 Japanese Yen 0.0114 0.0115 0.0121 0.0128 Euro in U.S. 1.1407 1.1334 1.0642 1.1101 Euro in Cdn 1.4767 1.4714 1.4279 1.4386Quotations provided by the Bank of Canada

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Chinas auto sales sink in July extending yearlong decline

BEIJING — China’s auto sales sank again in July, extending a yearlong contraction in the industry’s biggest global market.An industry group, the China Association of Automobile Manufacturers, says sales of sedans, SUVs and minivans declined 3.9% from a year earlier to 1.5 million.Sales of electric and hybrid vehicles, which had risen in recent months, declined despite government pressure on automakers to promote the technology.Consumer demand has been hurt by unease over Beijing’s tariff war with President Donald Trump and weakening Chinese economic growth.Auto sales for the seven months through July were off 12.8% at 11.6 million vehicles.The Associated Press read more

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Police blotter Shoplifters target Superstore

Norfolk OPP have released an image of a man wanted in connection to a theft at a Simcoe business.On Saturday evening police were called by employees of the Real Canadian Superstore reporting a theft.Police say a man entered the store and removed merchandise. He then exited the store and left in a black Hyundai in an unknown direction.Just a few hours after the male suspect left the store, a woman allegedly removed items from the same Simcoe store.Police say they received a complaint about the theft, and through investigation determined the woman attended the store and removed merchandise.A 59-year-old Norfolk County woman has been charged with theft under $5,000 and will appear in court at a later date.If anyone has any information or can identify the male suspect, they are being asked to contact the OPP at 1-888-310-1122.Neighbour dispute leads to chargeA 39-year-old Norfolk County man is facing trespassing charges after a dispute with a neighbour in Courland.Norfolk OPP say the man entered his neighbour’s property during a verbal confrontation.The man was subsequently charged with enter premises when entry prohibited contrary to the Trespass to Property Act.He was issued a provincial offences notice.Speed and alcohol don’t mixOn Friday night a driver was accused of speeding while impaired.Police say they were patrolling Blueline Road near Port Dover when the vehicle caught their attention. They stopped the vehicle at a to investigate.As a result a 61-year-old Norfolk man was charged with speeding, operation while impaired – blood alcohol concentration 80 plus, and driving motor vehicle with open container of liquor.He is scheduled to appear in court at a later date.Roadway litter leads to chargesAround noon on Saturday police were contacted by employees of the Norfolk County Roads Department reporting a hazardous condition.Police say a man dumped a large amount of debris in the middle of 12th Concession Road, North Walsingham, which caused serious hazards for other drivers.A 21-year-old Norfolk County man was charged with litter highway, contrary to the Highway Traffic Act.Police ask public to stop using 911 to report raccoonsA raccoon complaint is not an emergency.On Saturday afternoon police received an emergency 911 call to report a raccoon in a homeowner’s backyard.Homeowners who spot raccoons during the day are asked to contact a private animal removal service, not the police.“The OPP does not have the equipment to trap and house live animals or transport wild animals. Calling 911 for raccoons, tie up the phone lines at the communications center, waste taxpayer money, tie up law enforcement officers and threaten lives. A private animal removal service should be contacted instead,” said Norfolk OPP Inspector Joseph Varga.Suspended driver pulled overOn Saturday evening a 31-year-old Norfolk County man was pulled over after he caught the attention of officers patrolling Cockshutt Road in Townsend.As a result the man has been charged with speeding, operation while impaired – alcohol and drugs, driving while under suspension, failure to have insurance card, and driving a motor vehicle – no currently validated permit.Police looking to identify suspicious maleOn Sunday night a male resident was walking down Norfolk Street South in Simcoe when they were approached by a suspicious man in a vehicle.The man slowed down his vehicle to ask the resident a series of inappropriate questions.The unknown man is described as white, mid 30’s, dark trimmed goatee, wearing a dark baseball hat and dark sweater.The vehicle is described as a dark or black coloured Sports Utility Vehicle possibly a GMC Jimmy.If anyone has any information they are being asked to contact the OPP at 1-888-310-1122.Driver charged Automated licence-plate reading technology helped police pull a suspended driver off the road near Delhi. An officer with the Norfolk OPP was patrolling Highway 3 near Delhi when the device issued an alert for a problematic licence plate. The officer conducted a pull-over and discovered that the 27-year-old Norfolk man behind the wheel was under suspension. The pull-over occurred around 9:40 p.m. Thursday. The driver was charged accordingly and has a date to appear in the Ontario Court of Justice in Simcoe at a later date. read more

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New UN data points to devastating impact of AIDS in Africa

“The devastating impact of HIV/AIDS is rolling back decades of development progress in Africa,” UNAIDS Executive Director Dr. Peter Piot said. “Every element of African society – from teachers to soldiers to farmers – is under attack by AIDS.”HIV/AIDS is rapidly weakening economic stability in the fragile markets of sub-Saharan Africa, according to the UN agency. The rate of economic growth in sub-Saharan Africa has fallen by as much as 4 per cent because of AIDS, while labour productivity has been cut by up to 50 per cent in the hardest-hit countries. In Zambia, nearly two thirds of deaths among the managerial sector can be attributed to AIDS. By 2020, over 25 per cent of the workforce may be lost to the disease in some severely affected countries.In rural areas, agricultural output has been severely damaged by the deaths of 7 million farmers, UNAIDS said. Twenty per cent of rural families in Burkina Faso are estimated to have reduced their agricultural work or even abandoned their farms. With fewer people available to work the land, households are often forced to farm smaller plots or switch to less labour-intensive subsistence crops, which often have lower nutritional and market value.At the same time, AIDS is undermining national security in many hard-hit African nations. Ministries of defence in these countries report the prevalence of HIV averaging 20 to 40 per cent among soldiers, reaching as high as 50 to 60 per cent in countries where HIV/AIDS has been present for more than a decade.Meanwhile, the capacity of governments to serve their citizens is another casualty of the epidemic, as budgets shrink and civil servants are killed by AIDS. In Botswana, for example, the Government will lose a fifth of its public revenue by 2010 because of the epidemic. In Kenya, the disease accounts for up to three out of every four deaths in the police force. As essential services such as health, welfare, and justice falter, the most poor and vulnerable households endure the worst of the consequences, UNAIDS said. read more

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Five cool things that may convince smartphone buyers to pick up a

TORONTO – It’s not an iPhone killer and doesn’t absolutely demolish the best Android or Microsoft smartphones on the market. But the new BlackBerry Z10 is a huge step forward for the beleaguered company formerly known as Research in Motion, which is now simply calling itself BlackBerry.Here are five things that will impress BlackBerry aficionados and may sway smartphone consumers without entrenched allegiances to Apple or Android.1. Look and feelWhile not overwhelmingly distinct looking, the BlackBerry Z10 looks the part of a modern, svelte smartphone and once turned on, it responds well to touches and swipes. The screen is razor sharp and every movement feels fluid and fast, from cycling between the home screens to loading apps to browsing the web. The unique BlackBerry 10 gestures take some getting used to but once mastered, are quick and handy ways to multi-task between several apps and jump from doing one thing to another.2. BlackBerry HubFor users who have a work email account, one or two personal accounts and a slew of social media profiles — including Facebook, Twitter or LinkedIn — BlackBerry Hub is a handy way to keep track of them all. All messages and notifications from the various accounts get merged into one universal inbox with no need to separately log in to a bunch of different sites. You can quickly sneak a peek at the Hub’s contents by swiping from the left edge of the screen to the right. A small swipe begins to reveal just a bit of the Hub while a full swipe opens the inbox.3. Finally a decent selection of appsWhile still lagging far behind what’s available on iPhones and Android devices, BlackBerry World promises to have a robust selection of more than 70,000 apps to download at launch, including Facebook, Twitter, LinkedIn, Skype, Kindle, WhatsApp, Angry Birds, Songza, Slacker, Rdio, NHL.com, CBC, Tim Hortons, Air Canada, RBC and ING Direct. For users who aren’t constantly checking the app store for new games and programs to download and just need the basics, it’s likely BlackBerry World will have them covered. But there are some glaring omissions, including Netflix and Google Maps.4. Typing made easierThose who love BlackBerrys with QWERTY keyboards will want to wait for the Q10, expected out in April, but a lot of work went into making life bearable for users who will need to do a lot of typing on the Z10. It has a smart predictive text engine that senses what you’re trying to type and will autocorrect mistakes, as smartphone users are used to. But it also has a unique feature to speed up the typing process. As you input letters, it predicts what word you’re working toward and if it’s correct, you can quickly swipe at that word to have it filled in. For example, say you’ve inputted the word “I’m.” As you prepare to hit the next letter you may notice the word “going” appears above the G key, “just” is above J and “not” is above N. By swiping up from any of those letters the word is added to your message, saving you the keystrokes. Now a new set of predicted words is overlayed on the keyboard, potentially allowing you to construct a sentence or an entire message with just a series of swipes as opposed to typing out letter by letter.5. A cool camera appIt likely won’t be solely responsible for many sales, but the BlackBerry 10 camera app is a good example of an innovative twist on what could have been a ho-hum app. Smartphone cameras are great but still don’t produce the best shots every time, especially for those with have a less than steady grip when firing off photos. The BlackBerry 10 app takes a burst of photos and lets you easily scan through them to find the best of the bunch. The app can detect multiple faces in a frame and allows the user to individually pick the best frame for each person so everyone appears smiling and in focus. Five cool things that may convince smartphone buyers to pick up a new BlackBerry AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email by Michael Oliveira, The Canadian Press Posted Jan 30, 2013 2:48 pm MDT read more

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Solutions for Kenyas displaced must be determined by reality not politics –

“Causes of internal displacement are many and recurrent, and solutions must be pursued more rigorously for all IDPs in an equal manner,” said Chaloka Beyani, UN Special Rapporteur on the human rights of IDPs since November 2010, pointing at post-election violence, inter-communal clashes, evictions or natural disasters as major causes of displacement in Kenya.Kenya faces a range of humanitarian challenges. In addition to hosting the world largest refugee population of more than 550,000, there are also an estimated 300,000 IDPs, according to statistics compiled by the UN High Commissioner for Refugees (UNHCR). During his nine-day official visit to Kenya from 29 April to 7 May, Mr. Beyani met with representatives of the national and county governments, and other stakeholders, including IDPs, in Nairobi, Nakuru and Moyale.Following his visit to Moyale, where he saw burnt houses and destroyed schools leaving the displaced without a place to return to, Mr. Beyani stressed that “displaced pastoralists require special attention.” “The end of displacement cannot be determined by a political decision, but by reality,” Mr. Beyani said today at the end of his visit, “and durable solutions are only achieved once IDPs can enjoy their human rights without discrimination.” He welcomed the commitment and efforts by the Government of Kenya to resettle the displaced, but noted that lack of secure land tenure, children out of school, no access to health services, lack of livelihood opportunities and discrimination remain obstacles to lasting solutions. With this visit, Mr. Beyani followed up on the progress made since his last official mission carried out from 16 to 27 September 2011. Kenya’s Act on internal displacement recognizes these causes and requires immediate implementation,” the Special Rapporteur underscored. “This is not only a priority requirement to achieve durable solutions, but also for better preparedness.” Independent experts or special rapporteurs are appointed by the Geneva-based UN Human Rights Council to examine and report back on a country situation or a specific human rights theme. The positions are honorary and the experts are not UN staff, nor are they paid for their work. read more

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Cops Racial Slur Sprayed on LeBron James Los Angeles

The front gate of an L.A. home belonging to Cleveland Cavaliers’ LeBron James is freshly repainted Wednesday, May 31, 2017, after someone spray painted a racial slur on it. (AP Photo/Damian Dovarganes)LOS ANGELES (AP) — Police are investigating after someone spray painted a racial slur on the front gate of LeBron James’ home in Los Angeles on the eve of the NBA Finals.An unidentified person spray painted the N-word on the front gate of James’ home in the Brentwood neighborhood Wednesday morning, said Capt. Patricia Sandoval, a spokeswoman for the Los Angeles Police Department.James wasn’t at the home at the time, but the property manager told officers that they believe the incident was captured on surveillance video, Sandoval said. Police are investigating it as an act of vandalism and possible hate crime.Someone painted over the slur before officers arrived to investigate, Sandoval said.James bought the house in 2015 for over $20 million. The 9,440-square-foot home is not James’ primary residence, which is in Bath, Ohio.In 2015, James and his production company signed a developmental deal with Warner Bros. worth $15 million, an agreement that has him spending more time in Southern California. James spent several weeks in Los Angeles last summer working with his production company.James’ agent, Rich Paul, declined to comment on the vandalism.James and the Cleveland Cavaliers face the Golden State Warriors in the NBA Finals beginning Thursday night with Game 1 in Oakland. read more

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Ohio State footballs quarterback conundrum

With three games in the books for Ohio State football (2-1), the team’s quarterback situation isn’t any clearer than it was when former Buckeyes’ signal caller Terrelle Pryor departed the university on June 7. While he wouldn’t name a starter or say how snaps would be split between quarterbacks, coach Luke Fickell said at a Tuesday press conference that he would allow the quarterbacks, including redshirt freshman Taylor Graham and redshirt sophomore Ken Guiton, to continue to compete against one another in practice. Both senior Joe Bauserman and true freshman Braxton Miller are currently listed as the starters on the team’s weekly depth chart. “We don’t know what the plan is just yet,” Fickell said. “We’re going to have these guys compete. We know we need to get better. We had a hard time throwing the football.” On Saturday, Bauserman and Miller combined for 4-of-18 passing for 35 yards in OSU’s 24-6 loss against Miami. Miller, who threw an interception on his first pass attempt of the game, also fumbled to halt a Buckeyes drive in the fourth quarter. “I think that’s always something you worry about with a young guy,” Fickell said. “I think we had two fumbles all last year. I think it’s almost two times or three times as many (this season).” The team has lost three fumbles on the season. Fickell said he considered Millers’ turnovers a cause for concern. “We turned the ball over, that’s the obvious,” Fickell said. “We missed some shots, that’s obvious as well.” To say that the team missed some shots might be an understatement — Bauserman and Miller couldn’t connect with a single Buckeyes’ wide receiver in the contest. All four of the completed passes in Saturday’s loss were caught by running backs. Fickell said he didn’t consider using Graham or Guiton during the Miami game, adding that he didn’t see anything Graham or Guiton could have done differently from the Buckeyes’ quarterbacking tandem of Bauserman and Miller. Fickell said all four quarterbacks would get a chance to compete for playing time in this week’s practice. “We’ll probably give a lot more reps to all those guys (the quarterbacks),” he said. “I don’t know how it will work out exactly.” Fickell said he doesn’t place the blame for the offense’s lack of production on a single player and that the quarterbacks are receiving an undue amount of criticism. “We (have) to find a way to get our best 11 on the field,” Fickell said. “You focus on the quarterback. We focus on the tailback as well. We focus on the middle linebacker as well.” Fickell said that who plays at Ohio Stadium on Saturday will be determined by performance on the practice field throughout the week. “I don’t have the crystal ball,” Fickell said. “We know what we think. We’re going to see a battle (in practice) and we’re going to work at it.” read more

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New era of cut and paste humans close as man injected with

first_imgCancer cells hide themselves from the immune system by using the body's own safety mechanism against it  Layla Richards who was given designer immune cells to fight her cancer after all other attempts failed   Dr Lu You of Sichuan University in Chengdu has become the first to inject a man with CRISPR altered DNA  A world where DNA can be rewritten to fix deadly diseases has moved a step closer after scientists announced they had genetically-edited the cells of a human for the first time using a groundbreaking technique.A man in China was injected with modified immune cells which had been engineered to fight his lung cancer. Larger trials are scheduled to take place next year in the US and Beijing, which scientists say could open up a new era of genetic medicine.The technique used is called Crispr, which works like tiny molecular scissors snipping away genetic code and replacing it with new instructions to build better cells.It has been hailed the future of genetic editing because it is far cheaper, easier and more accurate than previous methods of replacing DNA code.British experts said the technique has the power to be ‘transformative’ for many diseases and said they were expecting to see ‘significant progress in the next few years.’ Cancer cells hide themselves from the immune system by using the body’s own safety mechanism against it  To give the immune system a better chance against cancer, the scientists took immune cells from the Chinese man and altered their DNA to remove the antenna, before increasing them in a lab and injecting them back into the patient’s bloodstream.Experts say it is effectively like cutting the brakes on the immune system.The initial phase one trial was carried out for safety, and doctors will be monitoring the man’s progress over the next six months. They are also planning to inject ten more people with genetically edited immune cells in the coming months.Dr Carl June, of the University of Pennsylvania in Philadelphia is also planning a trial in the US next year which will target three genes to treat cancer, while Peking University is planning Crispr trials for bladder, prostate and renal-cell in China next March.Prof June said the race had begun to get gene edited cells into the clinic.”I think this is going to trigger ‘Sputnik 2.0’, a biomedical duel on progress between China and the United States, which is important since competition usually improves the end product,” he told the journal Nature.Although there are no trials ongoing in the UK at the moment, British scientists have already been at the forefront of genetic editing techniques and are likely to start trials in the near future. Prof Andrew Sharrocks, of the faculty of biology, medicine and health at the University of Manchester said: “It is clear that with future improvements in the Crispr technology that the current study will be the first of many that attempt to harness this technology for treating human medical conditions.“Treating cancer is one of the uses but also potentially combating auto-immune type diseases including things like arthritis although a lot more work will be needed to bring that to fruition.“I would expect similar types of approaches to be pioneered in the next few years as the potential for using this technology in the medical sphere is high and potentially transformative.”In the case of the Chinese man, scientists led by oncologist Dr Lu You at Sichuan University in Chengdu, took immune cells from his blood and disabled a gene which holds the instructions to build a protein called PD-1.PD-1 works like an antenna, sitting on the surface of immune cells, and looking out for healthy cells, so that the immune system knows not to attack them.However cancer masquerades as a healthy cell  which is why it is often so deadly because the immune system does not see it as a threat.  Dr Lu You of Sichuan University in Chengdu has become the first to inject a man with CRISPR altered DNA  Layla Richards who was given designer immune cells to fight her cancer after all other attempts failed  Last year scientists at Great Ormond Street Hospital and University College London used a DNA snipping technique called TALEN to create designer immune cells which could hunt out and eradicate the leukaemia of 17 month old Layla Richards.It was so experimental and difficult that it had only ever been tried in mice, and specialists had to apply for emergency permission from health regulators and the hospital’s ethics committee.However Crispr is easier and is likely to make the practice more widespread for a range of conditions.Dr Adrian Thrasher of the Molecular Immunology Unit at UCL’s Institute of Child Health said:  “At the moment cancer is easiest and safest target as immune cells are modified in lab and given back.“But there are increasing numbers of applications for genetic disease which will be translated over coming years.”However some experts warned that there were still several hurdles to overcome. While scientists can manipulate the DNA of cells in the blood it is far harder when disease affect tissues.Dr Andrew Wood of the Institue of Genetics and Molecular Medicine at the University of Edinburgh, said: “It’s certainly true that the technical barriers to the effective application of somatic genome editing are being steadily removed, particularly in tissues such as the blood where patient cells can be removed and edited ex vivo before being reintroduced.“The major difficulty arises where diseases affect tissues such as the lung or the heart where ex vivo culture is problematic.“In this case, low editing efficiencies in situ may not be sufficient to yield clinical benefit. Of course, there is a huge global effort to overcome this problem, and it is reasonable to assume that there will be significant progress in the next few years.” Want the best of The Telegraph direct to your email and WhatsApp? 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Man rescued by RNLI crew after drifting mile out to sea in

first_imgThe crewman shouts to the drenched casualty, who is too big to fit in the dinghy and is wearing a hoodie and shorts: “Ey up fella, what are you doing out here?”He then radios to the Coastguard that the man was in a “£10 dinghy” and had no safety equipment.The man was then brought back safely to shore and was given safety advice.Dave Cocks, Lifeboat Operations Manager at Redcar RNLI, said: “This is a good example of the types of incident we repeatedly warn people about. “It was a reasonably pleasant evening but the wind and tide were a recipe for this to happen.”We believe the man was in his 30s.”He was dressed in only a hoodie and shorts, and he didn’t even fit in the toy dinghy. He was taken back to shore and given a stern safety warningCredit:RNLI The man drifted a mile out to seaCredit:RNLI A man who drifted a mile out to sea in a toy dinghy had to be rescued by a lifeboat crew as he battled against the wind and tide.The RNLI said if the alarm had not been raised they could have been recovering a dead body from the sea off Redcar.Video of the rescue showed a lifeboat crew member speeding out towards the Teesside Wind Farm in the North Sea at around 7.30pm on Monday. Man in dinghy Man arriving back to shore “If the alarm hadn’t been raised there was every likelihood he’d have drifted out of sight of land and we could well have been bringing a dead body back.” Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings.last_img read more

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